Welcome to the Muller Lab

where Dr. William Muller pioneers in developing genetically engineered mouse models (GEMMs) to study breast cancer at the Rosalind and Morris Goodman Cancer Institute.

 

Our group investigates mammary tumour initiation, development, progression and metastasis. We combine GEMMs, 2D, and 3D in vitro models with molecular and cellular techniques, bioinformatic approaches and analysis of clinical samples to identify critical signaling pathways and potential therapeutic targets in breast cancer, focusing on aggressive luminal tumours and those driven by the oncogene ErbB2/HER2.

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Learn more about our lab members, research, and open positions.